Long-Term Outcomes after Autologous Chondrocyte Implantation

Long-Term Evaluation of Autologous Chondrocyte Implantation

Purpose: The purpose of this study was to report the clinical outcomes of autologous chondrocyte implantation (ACI) procedures performed by a single orthopedic surgeon at a minimum of 7 years follow-up. Methods: A retrospective review of prospectively collected data was performed on 29 patients who underwent ACI of the knee between the years of 1998 and 2003. Prospective data were collected to ...

Improved outcomes with combined autologous chondrocyte implantation and patellofemoral osteotomy versus isolated autologous chondrocyte implantation.

PURPOSE To compare clinical outcomes of patients undergoing isolated patellofemoral autologous chondrocyte implantation (ACI) and ACI combined with patellofemoral realignment. METHODS A systematic review was performed by use of PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines/checklist. We searched PubMed, CINAHL (Cumulative Index to Nursing and Allied He...

Rehabilitation after autologous chondrocyte implantation in athletes.

Over the years a variety of cartilage restorative procedures have been developed for athletes to address focal, full-thickness cartilaginous defects in the knee joint, including microfracture, osteochondral autografts, osteochondral allografts, autologous chondrocyte implantation (ACI), and most recently, next-generation ACI involving scaffolds or cell-seeded scaffolds. Since its introduction, ...

Autologous Chondrocyte Implantation

Autologous chondrocyte implantation improves patellofemoral cartilage treatment outcomes.

Many patients with patellofemoral pain have multiple knee disorders, such as chondral defects, malalignment, and ligament insufficiency. I reviewed a treatment approach that included autologous chondrocyte implantation and biomechanical altering procedures to reduce impairment and symptoms in patients with patellofemoral lesions and biomechanical disorders. Thirty-eight patients (39 knees; mean...